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Centene Corporation Appoints Mark Eggert as Executive Vice President, Health Plans

Centene Corporation (NYSE: CNC) announced today that Mark Eggert has been appointed Executive Vice President, Health Plans, effective November 14, 2007. Mr. Eggert will report directly to Michael F. Neidorff, Centenes Chairman and Chief Executive Officer.

Mr. Eggert brings more than 25 years of relevant experience to Centene, most recently as the Associate Vice Chancellor and Deputy General Counsel for Washington University in St. Louis. In this role, he worked extensively on healthcare delivery systems, contracting and regulatory matters for the School of Medicine, which is closely affiliated with the top-ranked Barnes-Jewish Hospital and St. Louis Childrens Hospital. His portfolio also includes extensive experience with legal and strategic challenges in the public, academic and business sectors, including representing major healthcare providers and serving as an Assistant United States Attorney.

Mr. Neidorff stated, Mark Eggerts appointment exemplifies our commitment to operational excellence and adds another strong member to Centenes senior management team. He clearly understands the key factors for success in a managed care environment. This experience, in addition to his work in the public sector, brings an invaluable strategic perspective to help guide our health plans and our organization as it continues to grow and become more complex.

Mr. Eggert received an A.B., Magna Cum Laude, from Harvard College, a J.D., Cum Laude, from Harvard Law School and an M.B.A. from Washington University in St. Louis. He is a published author and accomplished speaker on a number of topics in the healthcare field.

About Centene Corporation

Centene Corporation is a leading multi-line healthcare enterprise that provides programs and related services to individuals receiving benefits under Medicaid, including the State Childrens Health Insurance Program (SCHIP) and Supplemental Security Income (SSI). The Company operates health plans in Florida, Georgia, Indiana, New Jersey, Ohio, South Carolina, Texas and Wisconsin. In addition, the Company contracts with other healthcare and commercial organizations to provide specialty services including behavioral health, health management, long-term care, managed vision, nurse triage, pharmacy benefits management and treatment compliance. Information regarding Centene is available via the Internet at www.centene.com.

Contacts:

Centene Corporation
Edmund E. Kroll, 212-759-0382
Senior Vice President, Finance and Investor Relations
or
Sandy McBride, 314-725-4477
Director, Corporate Communications

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