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Reminder: Centene's 5th Annual Investor Day -- June 5, 2007

Centene Corporation (NYSE: CNC) today announced that it will webcast its Fifth Annual Investor Day to be held on Tuesday, June 5, 2007, at The St. Regis Hotel in New York City. The meeting and webcast will begin promptly at 8:00 a.m. Eastern Time and end approximately at 12:30 p.m. Eastern Time. At the meeting, Centene expects Michael F. Neidorff, its Chairman and Chief Executive Officer, to make remarks regarding the Companys performance and future prospects.

Institutional investors and analysts interested in attending should contact Ed Kroll for additional information.

Interested parties may listen to the webcast by going to the Companys website at www.centene.com and accessing the Investor Relations section. A webcast replay will be available via Centenes IR section on its website immediately following the event.

About Centene Corporation

Centene Corporation is a leading multi-line healthcare enterprise that provides programs and related services to individuals receiving benefits under Medicaid, including the State Childrens Health Insurance Program (SCHIP) and Supplemental Security Income (SSI). The Company operates health plans in Georgia, Indiana, New Jersey, Ohio, Texas and Wisconsin. In addition, the Company contracts with other healthcare and commercial organizations to provide specialty services including behavioral health, disease management, long-term care, managed vision, nurse triage, pharmacy benefits management and treatment compliance. Information regarding Centene is available via the Internet at www.centene.com.

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